Home / Forums / Q&A from Webinar: Model-informed Drug Repurposing – Applications for COVID-19 (May 14) / Webinar Q: Unbound fraction in viral IC50 assays / Reply To: Webinar Q: Unbound fraction in viral IC50 assays
We must absolutely correct for it. Our screening approaches check unbound fraction concentration relative to the reported IC50s, as the in vitro assays are typically performed in serum-free media. Critical consideration.