Home / Forums / Q&A from Webinar: Model-informed Drug Repurposing – Applications for COVID-19 (May 14) / Webinar Q: Unbound fraction in viral IC50 assaysThis topic has 1 reply, 1 voice, and was last updated 11 months, 1 week ago by J WC.Webinar Q: Unbound fraction in viral IC50 assays J WC May 14, 2020 at 2:55 pmCould you please comment on the usefulness of determining unbound fraction in viral IC50 assays. Should we correct for it? J WC May 20, 2020 at 5:14 amWe must absolutely correct for it. Our screening approaches check unbound fraction concentration relative to the reported IC50s, as the in vitro assays are typically performed in serum-free media. Critical consideration. You must be logged in to reply to this topic.Log In Username: Password: Keep me signed inLogin