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Webinar Q: Unbound fraction in viral IC50 assays

  • J WC May 14, 2020 at 2:55 pm

    Could you please comment on the usefulness of determining unbound fraction in viral IC50 assays. Should we correct for it?

    J WC May 20, 2020 at 5:14 am

    We must absolutely correct for it. Our screening approaches check unbound fraction concentration relative to the reported IC50s, as the in vitro assays are typically performed in serum-free media. Critical consideration.

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