Impact of polymorphism?

  • How is genetic polymorphism likely to impact these derived models? If the impact is significant, can genetic differences be incorporated into the models?

    • This topic was modified 8 months ago by J WC.

    indeed we already know about some polymorphism affecting PK or cell entry or DDI so these are taken into account and are very important.

    In general, yes. If the impact has been previously incorporated in the PK analysis of the repurposed drugs, we’ll be able to use these knowledge in simulations

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