Home / Forums / Q&A from Webinar: Model-informed Drug Repurposing – Applications for COVID-19 (May 14) / Impact of polymorphism? / Reply To: Impact of polymorphism?
indeed we already know about some polymorphism affecting PK or cell entry or DDI so these are taken into account and are very important.
In general, yes. If the impact has been previously incorporated in the PK analysis of the repurposed drugs, we’ll be able to use these knowledge in simulations