Modeling and Simulation

What are examples of modeling and simulation?

Majority of drug approvals in the past several years have leveraged one or more technologies in the modeling and simulation toolbox.  These methods are used by companies to inform key drug development decisions and by regulators as a key component of clinical pharmacology and medical reviews. For companies, these tools support dose justification for general […]

What is modeling and simulation?

A model is a set of mathematical equations that describe observations. In some cases, the observations are plasma concentrations.  In other cases, it is intraocular pressure or enzyme inhibition. The “parameters” of the model are derived from the observations. A simulation is when you use a model to predict something. Instead of estimating parameters from […]